Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13098121 | 0.79 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL1063678 | 0.79 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL9223088 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL893345 | 0.77 | HSD17B10 (0.60) | ALDH1A1L3MBTL1HSD17B10HDAC8POLB | |
| SCHEMBL5255523 | 0.76 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL11217423 | 0.76 | HSD17B10 (0.55) | ALDH1A1L3MBTL1HSD17B10POLBHPGD | |
| SCHEMBL1520990 | 0.76 | IDO1 (0.50) | ALDH1A1MAPTHSD17B10HPGDKDM4E | |
| SCHEMBL28752859 | 0.74 | THRB (0.47) | ALDH1A1L3MBTL1MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL28149917 | 0.74 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL13034115 | 0.74 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458952-B | Heterocycle sulfamide derivatives and drug containing the heterocycle sulfamide derivatives | EA制药株式会社 | 2019-09-27 | — | — | CN | disclosed |
| CN-106458952-A | Heterocyclic sulfonamide derivative and medicine comprising same | EA制药株式会社 | 2017-02-22 | — | — | CN | disclosed |