Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20448183 | 0.86 | LMNA (0.46) | POLBLMNAGAAALDH1A1STING1 | |
| SCHEMBL2903444 | 0.86 | LMNA (0.46) | POLBLMNAGAAKMT2ASTING1 | |
| SCHEMBL13936345 | 0.86 | POLB (0.58) | POLBLMNAGAAKMT2AALDH1A1 | |
| SCHEMBL19183312 | 0.85 | LMNA (0.45) | POLBLMNAGAASTING1NPC1 | |
| SCHEMBL29451179 | 0.85 | LMNA (0.45) | POLBLMNAGAASTING1NPC1 | |
| SCHEMBL12370359 | 0.84 | POLB (0.47) | POLBLMNAGAAKMT2AALDH1A1 | |
| SCHEMBL8785540 | 0.80 | GAA (0.48) | POLBLMNAGAAKMT2AALDH1A1 | |
| SCHEMBL2342441 | 0.76 | GAA (0.47) | POLBLMNAGAAALDH1A1STING1 | |
| SCHEMBL2347739 | 0.76 | GAA (0.47) | POLBLMNAGAAKMT2ASTING1 | |
| SCHEMBL2903445 | 0.76 | GAA (0.41) | POLBLMNAGAAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368055-B | Preparation method of 3-fluoroalkyl-1-methylpyrazole-4-carboxylic acid | 宿迁市科莱博生物化学有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-106554311-B | The preparation method of 3- fluoro-alkyl -1- methylpyrazole -4- carboxylic acid | 常州市卜弋科研化工有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-108368055-A | The preparation method of 3- fluoro-alkyl -1- methylpyrazole -4- carboxylic acids | 苏威氟有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-106554311-A | The preparation method of 3- fluoro-alkyl -1- methylpyrazole -4- carboxylic acids | 常州市卜弋科研化工有限公司 | 2017-04-05 | — | — | CN | disclosed |