SCHEMBL2903445

SCHEMBL2903445

Cn1cc(OC(=O)O)c(C(F)(F)Cl)n1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
PDE10A Q9Y233 1/20 0.31
GLA P06280 1/20 0.30
KMT2A Q03164 1/20 0.30
NPC1 O15118 2/20 0.30
PKM P14618 2/20 0.30
PLA2G7 Q13093 1/20 0.30
MGLL Q99685 1/20 0.30
ABHD6 Q9BV23 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5274768 0.92 GAA (0.42) GAALMNAPOLBPDE10AGLA
SCHEMBL1406152 0.87 GAA (0.49) GAALMNAPOLBKMT2ANPC1
SCHEMBL16105736 0.79 GAA (0.42) GAALMNAPOLBGLAKMT2A
SCHEMBL3730626 0.76 GAA (0.48) GAALMNAPOLBNPC1PKM
SCHEMBL3402435 0.76 GAA (0.34) GAAPLA2G7MGLLABHD6
SCHEMBL28137017 0.76 POLB (0.49) GAALMNAPOLBKMT2ANPC1
SCHEMBL2903444 0.76 LMNA (0.46) GAALMNAPOLBKMT2ANPC1
SCHEMBL27615391 0.74 GAA (0.37) GAALMNAPOLBGLAKMT2A
SCHEMBL27596801 0.74 GAA (0.49) GAALMNAPOLBKMT2ANPC1
SCHEMBL3787937 0.73 GAA (0.48) GAALMNAPOLBNPC1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2236505-A1 Acylated aminopyridines and pyridazines as insecticides Bayer CropScience AG (DE) 2010-10-06 EP disclosed