Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.32 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.32 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2347739 | 0.90 | GAA (0.47) | LMNAPOLBGAAKMT2ASTING1 | |
| SCHEMBL28137017 | 0.86 | POLB (0.49) | LMNAPOLBGAAKMT2ASTING1 | |
| SCHEMBL20448183 | 0.86 | LMNA (0.46) | LMNAPOLBGAASTING1MGLL | |
| SCHEMBL19182678 | 0.86 | GAA (0.56) | LMNAPOLBGAASTING1TEAD1 | |
| SCHEMBL5720264 | 0.86 | POLB (0.41) | LMNAPOLBGAAKMT2ARAB9A | |
| SCHEMBL353314 | 0.86 | GAA (0.56) | LMNAPOLBGAASTING1TEAD1 | |
| SCHEMBL29451179 | 0.85 | LMNA (0.45) | LMNAPOLBGAASTING1NPC1 | |
| SCHEMBL19183312 | 0.85 | LMNA (0.45) | LMNAPOLBGAASTING1NPC1 | |
| Hydrochloric Acid SCHEMBL8355477 | 0.84 | GAA (0.55) | LMNAPOLBGAASTING1TEAD1 | |
| SCHEMBL1194663 | 0.83 | LMNA (0.46) | LMNAPOLBGAASTING1TEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179563-A1 | PROCESS FOR THE MANUFACTURE OF IMINIUM COMPOUNDS AND THEIR APPLICATION IN THE MANUFACTURE OF PYRAZOLE DERIVATIVES | SOLVAY SA (BE) | 2021-06-17 | — | — | US | disclosed |
| CN-108368055-B | Preparation method of 3-fluoroalkyl-1-methylpyrazole-4-carboxylic acid | 宿迁市科莱博生物化学有限公司 | 2021-04-16 | — | — | CN | disclosed |
| EP-3728195-A1 | PROCESS FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS | SOLVAY SA (BE) | 2020-10-28 | — | — | EP | disclosed |
| US-20200305431-A1 | PROCESS FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS | SOLVAY SA (BE) | 2020-10-01 | — | — | US | disclosed |
| CN-111587241-A | Method for producing iminium compound and use thereof for producing pyrazole derivative | 索尔维公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-111587242-A | Process for producing pyrazole compound | 索尔维公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-106467492-B | preparation method of polyfluoromethyl pyrazole compound, intermediate and preparation method | 联化科技(盐城)有限公司 | 2019-12-17 | — | — | CN | disclosed |
| US-10457645-B2 | Method for the preparation of 3-fluoroalkyl-1-methylpyrazol-4-carboxylic acid | CHANGZHOU KEYLAB BIOCHEMICAL CO., LTD. (CN) | 2019-10-29 | — | — | US | disclosed |
| US-20180273486-A1 | METHOD FOR THE PREPARATION OF 3-FLUOROALKYL-1-METHYLPYRAZOL-4-CARBOXYLIC ACID | CHANGZHOU KEYLAB BIOCHEMICAL CO., LTD. (CN) | 2018-09-27 | — | — | US | disclosed |
| EP-3357913-A1 | PREPARATION METHOD FOR 3-FLUOROALKYL-1-METHYLPYRAZOLE-4-CARBOXYLIC ACID | Solvay Fluor GmbH (DE) | 2018-08-08 | — | — | EP | disclosed |
| EP-2671874-B1 | Preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | SOLVAY (BE) | 2016-01-13 | — | — | EP | disclosed |
| US-8981116-B2 | Process for the preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | SOLVAY SA (BE) | 2015-03-17 | — | — | US | disclosed |
| EP-2671874-A1 | Preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | SOLVAY SA (BE) | 2013-12-11 | — | — | EP | disclosed |
| US-20130123510-A1 | Process for the preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | SOLVAY SA (BE) | 2013-05-16 | — | — | US | disclosed |
| CN-103068805-A | Preparation method of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic ester | SOLVAY | 2013-04-24 | — | — | CN | disclosed |
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
| EP-0623113-B1 | PYRAZOLE CARBOXANILIDE FUNGICIDES | MONSANTO CO (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5223526-A | For plants | MONSANTO COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993011117-A1 | PYRAZOLE CARBOXANILIDE FUNGICIDES | MONSANTO COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200305431-A1 | PROCESS FOR THE MANUFACTURE OF PYRAZOLE COMPOUNDS | CYP3A4, CYP3A43, CYP2E1 | LMNA 3401/4885POLB 2554/4885GAA 1946/4885 |
| US-10457645-B2 | Method for the preparation of 3-fluoroalkyl-1-methylpyrazol-4-carboxylic acid | PFAS, KCNK5, PCCA | LMNA 2675/4885POLB 2201/4885GAA 3562/4885 |
| US-20180273486-A1 | METHOD FOR THE PREPARATION OF 3-FLUOROALKYL-1-METHYLPYRAZOL-4-CARBOXYLIC ACID | PFAS, KCNK5, PCCA | LMNA 2675/4885POLB 2201/4885GAA 3562/4885 |
| US-20130123510-A1 | Process for the preparation of esters of 1-substituted-3-fluoroalkyl-pyrazole-4-carboxylic acids | CYP2F1, KHK, CYP4F3 | LMNA 1953/4885POLB 2256/4885GAA 1327/4885 |
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | LMNA 2262/4885POLB 2949/4885GAA 2373/4885 |
| US-20210179563-A1 | PROCESS FOR THE MANUFACTURE OF IMINIUM COMPOUNDS AND THEIR APPLICATION IN THE MANUFACTURE OF PYRAZOLE DERIVATIVES | CYP3A5, CYP3A4, CYP3A43 | LMNA 3744/4885POLB 2576/4885GAA 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.