Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28138836 | 0.82 | POLB (0.35) | PDGFRBPTPN2PTPN1LMNAHDAC4 | |
| SCHEMBL27516449 | 0.77 | MTNR1A (0.37) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27719444 | 0.76 | ALDH1A1 (0.39) | PDGFRBLMNAALDH1A1HTTKDM4E | |
| SCHEMBL28311081 | 0.76 | KDM4E (0.36) | PTPN1LMNAEGFRALDH1A1KDM4E | |
| SCHEMBL28158502 | 0.75 | HTR2C (0.40) | HTR6 | |
| Hydrochloric Acid SCHEMBL28141251 | 0.74 | ALDH1A1 (0.38) | PDGFRBLMNAALDH1A1HTTKDM4E | |
| SCHEMBL4625094 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL21250753 | 0.73 | PDGFRB (0.46) | PDGFRBPTPN2PTPN1GPR3LMNA | |
| SCHEMBL28138814 | 0.71 | MGLL (0.34) | LMNAALDH1A1HTTKDM4EHPGD | |
| SCHEMBL30353863 | 0.69 | GAA (0.62) | PDGFRBPTPN2PTPN1GPR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110776494-B | Benzyl piperidine-benzimidazole derivative or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2021-01-05 | — | — | CN | claimed |
| CN-110776494-A | Benzyl piperidine-benzimidazole derivative or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2020-02-11 | — | — | CN | claimed |
| CN-110776494-B | Benzyl piperidine-benzimidazole derivative or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-110904041-A | Medicine for promoting hemopoietic stem cell expansion and application thereof | 中山大学 | 2020-03-24 | — | — | CN | disclosed |
| CN-110776494-A | Benzyl piperidine-benzimidazole derivative or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2020-02-11 | — | — | CN | disclosed |
| CN-106573896-B | Fluoroalkylating agents | KUMIAI CHEMICAL INDUSTRY CO.,LTD. (JP) | 2019-11-01 | — | — | CN | disclosed |
| CN-106573896-A | Fluoroalkylating agents | 庵原化学工业株式会社 | 2017-04-19 | — | — | CN | disclosed |