Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27719444 | 0.78 | ALDH1A1 (0.39) | KDM4EALOX15MAPTMEN1KMT2A | |
| SCHEMBL27859623 | 0.77 | ACHE (0.55) | ACHE | |
| Hydrochloric Acid SCHEMBL28141251 | 0.76 | ALDH1A1 (0.38) | KDM4EALOX15MAPTMEN1KMT2A | |
| SCHEMBL28138277 | 0.76 | PDGFRB (0.38) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL27719437 | 0.73 | L3MBTL1 (0.47) | MAPTKMT2ACYP3A4ALDH1A1LMNA | |
| SCHEMBL28311915 | 0.70 | ACHE (0.42) | ACHE | |
| SCHEMBL27980007 | 0.70 | PDE4A (0.32) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27841613 | 0.69 | ESR1 (0.36) | KDM4ETP53ALOX15CYP1A2CYP3A4 | |
| SCHEMBL27859215 | 0.69 | MEN1 (0.34) | KDM4ETP53ALOX15MAPTMEN1 | |
| SCHEMBL28875499 | 0.66 | ACHE (0.41) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988093-A | The aminated compounds for inhibiting SSAO/VAP-1 and its application in medicine | 广东东阳光药业有限公司 | 2019-07-09 | — | — | CN | disclosed |