SCHEMBL28138693

SCHEMBL28138693

CCCN(c1ccc(C)cc1)c1ccc(C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43
KCNH2 Q12809 1/20 0.41
ACHE P22303 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP2C19 P33261 1/20 0.39
RXRA P19793 2/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35
MAPT P10636 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
MCHR1 Q99705 1/20 0.34
DHFR P00374 1/20 0.34
EGFR P00533 2/20 0.34
PDGFRB P09619 2/20 0.34
KDR P35968 2/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6882172 0.89 ACHE (0.52) ALDH1A1TSHRPOLBKMT2AKCNH2
SCHEMBL16715076 0.87 ALDH1A1 (0.52) ALDH1A1TSHRACHETDP1CYP2C19
SCHEMBL800068 0.84 MCHR1 (0.46) ALDH1A1TSHRKCNH2CYP2C19MCHR1
SCHEMBL11331999 0.82 MCHR1 (0.49) ALDH1A1TSHRKCNH2MCHR1RAB9A
SCHEMBL11342192 0.82 MCHR1 (0.49) ALDH1A1TSHRKCNH2MCHR1RAB9A
SCHEMBL7153293 0.80 MTNR1A (0.47) ALDH1A1TSHRKCNH2TDP1CYP2C19
SCHEMBL516400 0.80 CYP2C19 (0.48) ALDH1A1TSHRKCNH2ACHETDP1
SCHEMBL516438 0.79 ALDH1A1 (0.50) ALDH1A1TSHRKCNH2ACHETDP1
SCHEMBL17753328 0.79 HPGD (0.52) ALDH1A1TSHRPOLBKMT2ATDP1
SCHEMBL17660041 0.79 DHFR (0.46) ALDH1A1KMT2AKCNH2TDP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106574059-A Plastic substrate 株式会社LG化学 2017-04-19 CN disclosed