Methylene Chloride

Methylene Chloride

SCHEMBL28138917

CS(=O)(=O)c1ccc(C(=O)Cl)c([N+](=O)[O-])c1.ClCCl

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
ALDH3A1 P30838 3/20 0.46
MAPT P10636 4/20 0.45
MEN1 O00255 2/20 0.45
RAB9A P51151 2/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 1/20 0.45
LMNA P02545 3/20 0.44
GAA P10253 1/20 0.44
FLT1 P17948 2/20 0.43
FLT4 P35916 2/20 0.43
KDR P35968 2/20 0.43
NPC1 O15118 1/20 0.43
MITF O75030 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
CCR6 P51684 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
PKM P14618 1/20 0.41
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2084156 0.95 ALDH1A1 (0.51) ALDH1A1ALDH3A1MAPTMEN1RAB9A
SCHEMBL30595897 0.95 ALDH1A1 (0.51) ALDH1A1ALDH3A1MAPTMEN1RAB9A
Hydrochloric Acid SCHEMBL28740577 0.94 ALDH1A1 (0.50) ALDH1A1ALDH3A1MAPTMEN1RAB9A
SCHEMBL18287473 0.82 ALDH1A1 (0.48) ALDH1A1ALDH3A1MAPTMEN1RAB9A
SCHEMBL1202449 0.81 ALDH1A1 (0.56) ALDH1A1ALDH3A1MAPTMEN1RAB9A
Hydrogen Peroxide SCHEMBL28991385 0.81 ALDH1A1 (0.56) ALDH1A1ALDH3A1MAPTMEN1RAB9A
SCHEMBL18287474 0.81 ALDH3A1 (0.53) ALDH1A1ALDH3A1MAPTMEN1RAB9A
SCHEMBL9517119 0.81 FLT1 (0.47) ALDH1A1FLT1FLT4KDRVCAM1
SCHEMBL21385706 0.81 ALDH1A1 (0.49) ALDH1A1ALDH3A1MAPTMEN1RAB9A
SCHEMBL11779143 0.80 CA2 (0.63) ALDH1A1MAPTKMT2AGAAFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106565556-A Synthetic process of mesotrione 湖北广富林生物制剂有限公司 2017-04-19 CN claimed
CN-106565560-A Synthesis process of mesotrione 湖北广富林生物制剂有限公司 2017-04-19 CN claimed
CN-106748918-A A kind of synthesis technique of mesotrione 湖北广富林生物制剂有限公司 2017-05-31 CN disclosed
CN-106748919-A A kind of synthesis technique of mesotrione 湖北广富林生物制剂有限公司 2017-05-31 CN disclosed
CN-106565556-A Synthetic process of mesotrione 湖北广富林生物制剂有限公司 2017-04-19 CN disclosed
CN-106565560-A Synthesis process of mesotrione 湖北广富林生物制剂有限公司 2017-04-19 CN disclosed