Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26646427 | 0.88 | GABRA1 (0.37) | KCNA5MEN1NPC1HTTRAB9A | |
| SCHEMBL28289842 | 0.86 | L3MBTL1 (0.40) | KCNA5HIF1AMEN1NPC1HTT | |
| SCHEMBL27893627 | 0.85 | KCNA5 (0.34) | KCNA5MEN1NPC1HTTRAB9A | |
| SCHEMBL28139529 | 0.83 | ALDH1A1 (0.41) | HIF1APOLBHTTKMT2AATM | |
| SCHEMBL7110903 | 0.81 | CTSS (0.37) | KCNA5KMT2AALDH1A1 | |
| SCHEMBL27670092 | 0.81 | ALDH1A1 (0.41) | KCNA5CYP2C19HIF1APOLBMEN1 | |
| SCHEMBL27897121 | 0.81 | TSHR (0.38) | HTTTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL28637275 | 0.80 | TSHR (0.47) | POLBMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL5934008 | 0.78 | LMNA (0.46) | CYP2C19HIF1AMEN1NPC1HTT | |
| SCHEMBL28079344 | 0.78 | HPGD (0.39) | MEN1NPC1HTTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |