Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iophendylate SCHEMBL28086374 | 0.86 | KDM4E (0.36) | ALDH1A1KDM4EL3MBTL1LTA4HNAMPT | |
| SCHEMBL492664 | 0.83 | CYP4F2 (0.46) | ALDH1A1PPARGCYP4F2CYP4A11NAMPT | |
| SCHEMBL3936803 | 0.83 | CYP4F2 (0.46) | ALDH1A1PPARGCYP4F2CYP4A11NAMPT | |
| Propyliodone SCHEMBL38586 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL8562391 | 0.74 | CYP4F2 (0.43) | ALDH1A1KDM4EL3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL27599795 | 0.66 | CSNK1E (0.37) | ALDH1A1PPARGMEN1KMT2A | |
| Iophendylate SCHEMBL492663 | 0.65 | CYP4F2 (0.42) | ALDH1A1KDM4ECYP4F2CYP4A11NAMPT | |
| SCHEMBL5271602 | 0.65 | DGKA (0.69) | ALDH1A1L3MBTL1KMT2ATDP1 | |
| SCHEMBL5273301 | 0.65 | DGKA (0.69) | ALDH1A1L3MBTL1KMT2ATDP1 | |
| SCHEMBL20564422 | 0.65 | DGKA (0.69) | ALDH1A1L3MBTL1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |