Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propyliodone SCHEMBL28142146 | 0.86 | ALDH1A1 (0.36) | KDM4EPOLBALDH1A1L3MBTL1MEN1 | |
| Iophendylate SCHEMBL492663 | 0.82 | CYP4F2 (0.42) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| Iophendylate SCHEMBL15532920 | 0.77 | MAPT (0.41) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Propyliodone SCHEMBL38586 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL3170654 | 0.66 | LTA4H (0.52) | SMN1; SMN2LTA4HALDH2MAOAMAOB | |
| SCHEMBL492664 | 0.66 | CYP4F2 (0.46) | ALDH1A1KMT2ATDP1SMN1; SMN2NAMPT | |
| SCHEMBL3936803 | 0.66 | CYP4F2 (0.46) | ALDH1A1KMT2ATDP1SMN1; SMN2NAMPT | |
| SCHEMBL20564422 | 0.65 | DGKA (0.69) | ALDH1A1L3MBTL1KMT2ATDP1LMNA | |
| SCHEMBL5273301 | 0.65 | DGKA (0.69) | ALDH1A1L3MBTL1KMT2ATDP1LMNA | |
| SCHEMBL5271602 | 0.65 | DGKA (0.69) | ALDH1A1L3MBTL1KMT2ATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |