Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | PPIA | P62937 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8282998 | 0.83 | CA12 (0.42) | CA12CA14CA2P2RX7CNR2 | |
| SCHEMBL13010604 | 0.81 | CA2 (0.41) | CA12CA14CA2P2RX7CNR2 | |
| SCHEMBL28142895 | 0.78 | CA12 (0.36) | CA12CA14CA2P2RX7CNR2 | |
| SCHEMBL22380429 | 0.76 | CTSL (0.35) | CA12CA14CA2P2RX7CTSL | |
| SCHEMBL28143617 | 0.75 | P2RX7 (0.35) | CA12CA14CA2P2RX7CNR2 | |
| SCHEMBL3022379 | 0.75 | CA12 (0.37) | CA12CA14CA2P2RX7CNR2 | |
| SCHEMBL22633505 | 0.75 | CA12 (0.36) | CA12CA14CA2P2RX7CTSL | |
| SCHEMBL6887591 | 0.74 | APLNR (0.37) | CA12CA14CA2P2RX7CTSL | |
| SCHEMBL428722 | 0.74 | P2RX7 (0.38) | CA2P2RX7CTSLPPIAAPLNR | |
| SCHEMBL25568153 | 0.74 | CNR2 (0.37) | CA12CA14CA2P2RX7CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104854087-B | Indole carboxamide derivatives as P2X receptor antagonists | 埃科特莱茵药品有限公司 | 2017-03-22 | — | — | CN | disclosed |