Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL28144340 | 0.89 | — | — | |
| Benzene SCHEMBL28024640 | 0.87 | BLM (0.50) | LMNAFFAR3LCKFYNHSD17B10 | |
| Acetic Acid SCHEMBL7172246 | 0.85 | — | — | |
| Benzene SCHEMBL28109076 | 0.82 | ALDH1A1 (0.56) | LMNAFFAR3LCKFYNHSD17B10 | |
| Benzene SCHEMBL10771333 | 0.80 | LMNA (0.67) | LMNAFFAR3LCKFYNHSD17B10 | |
| Benzene SCHEMBL11765690 | 0.80 | LMNA (0.67) | LMNAFFAR3LCKFYNHSD17B10 | |
| Benzene SCHEMBL11545210 | 0.80 | LMNA (0.67) | LMNAFFAR3LCKFYNHSD17B10 | |
| Benzene SCHEMBL107628 | 0.80 | ALDH1A1 (0.47) | HSD17B10ALDH1A1TDP1SMN1; SMN2CA4 | |
| Benzene SCHEMBL11307929 | 0.80 | LMNA (0.67) | LMNAFFAR3LCKFYNHSD17B10 | |
| Benzene SCHEMBL312284 | 0.80 | LMNA (0.67) | LMNAFFAR3LCKFYNHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106748914-B | O- benzene sulfonyl -4- trifluoromethyl salicylamide compound and its application in preparation anti-gastric cancer medicament | 浙江工业大学 | 2019-04-09 | — | — | CN | disclosed |
| CN-106588716-B | O- benzene sulfonyl -4- trifluoromethyl salicylamide compound and its preparing the application in anti-lung-cancer medicament | 浙江工业大学 | 2019-04-09 | — | — | CN | disclosed |
| CN-106748914-A | The trifluoromethyl salicylamide compound of O benzene sulfonyls 4 and its application in anti-gastric cancer medicament is prepared | 浙江工业大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-106588716-A | O-phenylsulfonyl-4-trifluoromethyl salicylamide compound and application thereof in preparing medicine against lung cancer | 浙江工业大学 | 2017-04-26 | — | — | CN | disclosed |