Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 14/20 | 0.48 |
| ▸ | PPARD | Q03181 | 13/20 | 0.48 |
| ▸ | PPARG | P37231 | 12/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28146169 | 0.90 | SORT1 (0.54) | SORT1PPARAPPARDPPARGMLYCD | |
| SCHEMBL28145229 | 0.86 | SORT1 (0.53) | SORT1PPARAPPARDPPARGNR1H4 | |
| SCHEMBL28146165 | 0.83 | KMT2A (0.48) | PPARG | |
| SCHEMBL28145221 | 0.83 | LMNA (0.61) | SORT1MLYCD | |
| SCHEMBL17339230 | 0.82 | SORT1 (0.52) | SORT1PPARAPPARDPPARGEPHX2 | |
| SCHEMBL6544791 | 0.81 | SORT1 (0.56) | SORT1PPARAPPARDPPARGEPHX2 | |
| SCHEMBL28145224 | 0.80 | LSS (0.63) | PPARAPPARGEPHX2NR1H4MLYCD | |
| SCHEMBL28146179 | 0.79 | CNR2 (0.45) | SORT1PPARGEPHX2 | |
| SCHEMBL25376744 | 0.78 | CLPP (0.52) | SORT1PPARAPPARDPPARGMLYCD | |
| SCHEMBL28328407 | 0.78 | MLYCD (0.58) | MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661035-B | The Pyrazolopyrimidine derivative of inhibitor as bruton's tyrosine kinase | 洛克索肿瘤学股份有限公司 | 2019-11-19 | — | — | CN | disclosed |
| CN-106661035-A | Pyrazolopyrimidine derivatives as inhibitors of bruton's tyrosine kinase | 莱德克斯制药公共有限公司 | 2017-05-10 | — | — | CN | disclosed |