Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 7/20 | 0.58 |
| ▸ | CA2 | P00918 | 7/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287798 | 0.90 | CA2 (0.64) | CA9CA2CYP2A6CA1CA12 | |
| SCHEMBL28145358 | 0.80 | CYP2A6 (0.49) | CA9CA2CYP2A6CA1CA12 | |
| SCHEMBL28844211 | 0.80 | CDK8 (0.46) | CA9CA2CA1CA12CDK8 | |
| SCHEMBL28844052 | 0.77 | MAOA (0.60) | CA9CA2CA1CA12CDK8 | |
| SCHEMBL11992658 | 0.77 | MAOA (0.52) | CA9CA2CA1CA12CDK8 | |
| SCHEMBL13035338 | 0.76 | CYP2A6 (1.00) | CYP2A6CHEK2CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL2561753 | 0.74 | CDK8 (0.48) | CA9CA2CA1CA12CDK8 | |
| SCHEMBL14075569 | 0.74 | CA9 (0.70) | CA9CA2CYP2A6CA1CA12 | |
| SCHEMBL28145248 | 0.74 | CA9 (0.64) | CA9CA2CA1CA12CDK8 | |
| SCHEMBL28146304 | 0.74 | CA9 (0.54) | CA9CA2CA1CA12CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334527-B | Sulfonamide compounds and uses as tnap inhibitors | 桑福德-伯纳姆医学研究院 | 2017-05-24 | — | — | CN | disclosed |