Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 8/20 | 0.64 |
| ▸ | CA2 | P00918 | 7/20 | 0.64 |
| ▸ | CA1 | P00915 | 6/20 | 0.64 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.64 |
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | TTK | P33981 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844052 | 0.82 | MAOA (0.60) | CA9CA2CA1CA12MAOB | |
| SCHEMBL28145245 | 0.78 | KIF11 (0.56) | CA9CA2CA1CA12PTGES2 | |
| SCHEMBL31287698 | 0.76 | CA2 (0.57) | CA9CA2CA1CA13CA12 | |
| SCHEMBL28163875 | 0.76 | CA2 (0.57) | CA9CA2CA1CA13CA12 | |
| SCHEMBL11992658 | 0.76 | MAOA (0.52) | CA9CA2CA1CA13CA12 | |
| SCHEMBL28032548 | 0.75 | CA2 (0.73) | CA9CA2CA1CA13CA12 | |
| SCHEMBL28145286 | 0.74 | CA9 (0.58) | CA9CA2CA1CA13CA12 | |
| SCHEMBL22507033 | 0.73 | MMP3 (0.56) | CA9CA2CA1CA12CYP11B2 | |
| SCHEMBL2561753 | 0.73 | CDK8 (0.48) | CA9CA2CA1CA13CA12 | |
| SCHEMBL14075569 | 0.73 | CA9 (0.70) | CA9CA2CA1CA13CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334527-B | Sulfonamide compounds and uses as tnap inhibitors | 桑福德-伯纳姆医学研究院 | 2017-05-24 | — | — | CN | disclosed |