Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 8/20 | 0.45 |
| ▸ | CA2 | P00918 | 8/20 | 0.44 |
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674154 | 0.88 | KAT6A (0.53) | CDK8CA9CA2CA1CA12 | |
| SCHEMBL28145286 | 0.80 | CA9 (0.58) | CDK8CA9CA2CA1CA12 | |
| SCHEMBL28145358 | 0.74 | CYP2A6 (0.49) | CDK8CA9CA2CA1CA12 | |
| SCHEMBL28844052 | 0.74 | MAOA (0.60) | CDK8CA9CA2CA1CA12 | |
| SCHEMBL11992658 | 0.74 | MAOA (0.52) | CDK8CA9CA2CA1CA12 | |
| SCHEMBL27999964 | 0.73 | ALPL (0.59) | CA9CA2CA1CA12CA3 | |
| SCHEMBL28282439 | 0.73 | CA2 (0.52) | CA9CA2CA1CA12CA3 | |
| SCHEMBL2561753 | 0.71 | CDK8 (0.48) | CDK8CA9CA2CA1CA12 | |
| SCHEMBL14075569 | 0.71 | CA9 (0.70) | CDK8CA9CA2CA1CA12 | |
| SCHEMBL28146304 | 0.71 | CA9 (0.54) | CDK8CA9CA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334527-B | Sulfonamide compounds and uses as tnap inhibitors | 桑福德-伯纳姆医学研究院 | 2017-05-24 | — | — | CN | disclosed |