Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | IL2 | P60568 | 1/20 | 0.46 |
| ▸ | RORA | P35398 | 2/20 | 0.43 |
| ▸ | RORB | Q92753 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5616332 | 0.82 | PTGS2 (0.50) | RORC | |
| SCHEMBL3708513 | 0.76 | CES2 (0.48) | RORCSCN9ARORB | |
| SCHEMBL2390396 | 0.76 | KCNJ5 (0.49) | RORCSCN9ARORBRIPK1SLC22A12 | |
| Hydrochloric Acid SCHEMBL4371024 | 0.75 | CES2 (0.47) | RORCSCN9ARORB | |
| SCHEMBL27897141 | 0.74 | RORB (0.45) | SCN9ARORBRIPK1SLC22A12HTR3E | |
| SCHEMBL9890806 | 0.73 | RORB (0.42) | SCN9ARORBRIPK1RAB9ASLC22A12 | |
| SCHEMBL2773940 | 0.72 | AURKA (0.43) | RORCSCN9ARORBRIPK1RAB9A | |
| SCHEMBL30463470 | 0.72 | BCAT2 (0.53) | RAB9A | |
| SCHEMBL5670647 | 0.72 | DHODH (0.57) | RORCIL2RAB9A | |
| SCHEMBL8659324 | 0.71 | PTGS2 (0.46) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109906216-A | Histone acetyltransferases activator and combinations thereof and purposes | 纽约哥伦比亚大学理事会 | 2019-06-18 | — | — | CN | disclosed |
| CN-106604913-A | Histone acetyltransferase activators and uses thereof | 纽约哥伦比亚大学理事会 | 2017-04-26 | — | — | CN | disclosed |