SCHEMBL28146641

SCHEMBL28146641

NC1=Cc2ccccc2C1O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
HTR2A P28223 1/20 0.34
CYP2D6 P10635 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
HTR6 P50406 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL27370011 0.98 MAOA (0.35) MAOAMAOBHTR2ACYP2D6MEN1
SCHEMBL15535721 0.76 MAOA (0.39) MAOAMAOBHTR2ACYP2D6MEN1
SCHEMBL8531996 0.74 MAOA (0.38) MAOAMAOBHTR2ACYP2D6MEN1
SCHEMBL30424597 0.74 HTR2A (0.38) HTR2AMEN1GAAKMT2AHTR6
SCHEMBL28742878 0.73 MAOA (0.41) MAOAMAOBHTR2ACYP2D6MEN1
SCHEMBL27428432 0.73 MAOA (0.37) MAOAMAOBHTR2ACYP2D6GAA
SCHEMBL12629758 0.73 MAOA (0.37) MAOAMAOBHTR2ACYP2D6MEN1
SCHEMBL5574454 0.73 DRD2 (0.40) HTR2AHTR6
SCHEMBL27822069 0.73 MAOA (0.37) MAOAMAOBHTR2ACYP2D6MEN1
SCHEMBL27316211 0.73 MAOA (0.37) MAOAMAOBHTR2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113501843-B Synthesis method of trivalent phosphorus substituted amine compound 兰州大学 2023-06-02 CN claimed
CN-121318804-A Method for preparing chiral sulfinate by asymmetric oxidation 西安近代化学研究所 2026-01-13 CN disclosed
US-20250092312-A1 ANTIPOLYMERANT COMPOSITIONS WITH BENZOQUINONE OR NAPHTHOQUINONE AND OXYGENATED AMINOPHENOL AND METHODS OF USING ECOLAB USA INC. 2025-03-20 US disclosed
WO-2025059441-A1 ANTIPOLYMERANT COMPOSITIONS WITH BENZOQUINONE OR NAPHTHOQUINONE AND OXYGENATED AMINOPHENOL AND METHODS OF USING ECOLAB USA INC. (US) 2025-03-20 WO disclosed
CN-117756746-A Preparation method of cyclic sulfonamide compound 上海工程技术大学 2024-03-26 CN disclosed
CN-110267944-B Compounds useful for the treatment of gastrointestinal disorders 阿德利克斯股份有限公司 2024-03-08 CN disclosed
US-11866631-B2 Oxygenated aminophenol compounds and methods for preventing monomer polymerization ECOLAB USA INC. (US) 2024-01-09 US disclosed
CN-113680386-B N-heterocyclic carbene-squaraine difunctional catalyst and preparation method thereof 深圳湾实验室坪山生物医药研发转化中心 2023-08-11 CN disclosed
CN-113731488-B N-heterocyclic carbene-urea difunctional catalyst and preparation method thereof 深圳湾实验室坪山生物医药研发转化中心 2023-08-04 CN disclosed
CN-113680385-B N-heterocyclic carbene-thiourea bifunctional group catalyst and preparation method and application thereof 深圳湾实验室坪山生物医药研发转化中心 2023-05-23 CN disclosed
WO-2023023880-A1 NITROGEN HETEROCYCLIC CARBENE-UREA BIFUNCTIONAL CATALYST AND PREPARATION METHOD THEREFOR 深圳湾实验室坪山生物医药研发转化中心 2023-03-02 WO disclosed
CN-106674400-A Ethylene copolymer having excellent processability 韩华道达尔有限公司 2017-05-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11866631-B2 Oxygenated aminophenol compounds and methods for preventing monomer polymerization HPD, DNPEP, PAH MAOA 46/4885MAOB 64/4885HTR2A 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.