Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17423083 | 0.79 | SCN7A (0.51) | MRGPRX4NPC1S1PR5HTR1ASLC6A2 | |
| SCHEMBL15669058 | 0.74 | MRGPRX4 (0.74) | MRGPRX4MEN1KMT2ANPC1APP | |
| SCHEMBL9706350 | 0.74 | L3MBTL1 (0.49) | MRGPRX4ALDH1A1NPC1SGMS2KDM1A | |
| SCHEMBL341109 | 0.72 | SGMS2 (0.62) | FAAHCNR1CNR2MEN1KMT2A | |
| SCHEMBL28551712 | 0.72 | FOLH1 (0.54) | MRGPRX4MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL19196780 | 0.70 | LRRK2 (0.54) | MRGPRX4MEN1KMT2AALDH1A1SGMS2 | |
| SCHEMBL4939266 | 0.70 | MAOB (0.60) | MEN1KMT2AALDH1A1NPC1MCL1 | |
| SCHEMBL15129536 | 0.70 | FOLH1 (0.55) | MRGPRX4MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL4437175 | 0.69 | RXRA (0.52) | NPC1FOLH1MCL1MAPTL3MBTL1 | |
| SCHEMBL8658870 | 0.69 | MAOB (0.55) | MEN1KMT2AALDH1A1NPC1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715418-A | Therapeutic compounds and methods of use thereof | 基因泰克公司 | 2017-05-24 | — | — | CN | disclosed |