SCHEMBL4437175

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL590872	0.89	MCL1 (0.48)	RXRARXRBRXRGMCL1FFAR4
	SCHEMBL3112448	0.88	RXRA (0.59)	RXRARXRBRXRGMCL1FFAR4
	SCHEMBL12659976	0.86	GLRA1 (0.57)	RXRARXRBRXRGMCL1FFAR4
	SCHEMBL21327204	0.84	MCL1 (0.54)	RXRARXRBRXRGMCL1FFAR4
	SCHEMBL24983814	0.84	ALDH1A1 (0.54)	RXRARXRBRXRGMCL1FFAR4
	SCHEMBL7825765	0.82	CTSV (0.58)	RXRARXRBRXRGMCL1SMN1; SMN2
	SCHEMBL15080744	0.81	SMN1; SMN2 (0.56)	RXRARXRBRXRGMAPTTDP1
	SCHEMBL71526	0.81	RXRA (0.58)	RXRARXRBRXRGMCL1FFAR4
	SCHEMBL21327456	0.81	LRRK2 (0.57)	MCL1FFAR4MAPTTDP1L3MBTL1
	SCHEMBL2327231	0.81	MAOB (0.57)	MCL1L3MBTL1SMN1; SMN2MAOBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.