Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18302448 | 0.85 | MAPT (0.52) | MEN1KMT2ARAB9ANPC1DAO | |
| SCHEMBL4703482 | 0.85 | DAO (0.55) | MEN1KMT2ACA2DAOMAPT | |
| SCHEMBL25399545 | 0.83 | KMT2A (0.54) | MEN1KMT2ACA2MAPTMAPK1 | |
| SCHEMBL3055932 | 0.83 | MEN1 (0.37) | MEN1KMT2ARAB9ANPC1CA2 | |
| SCHEMBL25399448 | 0.83 | OPRD1 (0.45) | MEN1KMT2ARAB9ACA2DAO | |
| SCHEMBL28148274 | 0.80 | KMT2A (0.43) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL24579380 | 0.80 | ALDH1A1 (0.38) | MEN1KMT2ARAB9ACA2DAO | |
| Hydrochloric Acid SCHEMBL30515341 | 0.77 | MEN1 (0.37) | MEN1KMT2ARAB9ANPC1CA2 | |
| SCHEMBL8627970 | 0.77 | HPGD (0.47) | MEN1KMT2ARAB9ANPC1CA2 | |
| SCHEMBL8632472 | 0.75 | MAPT (0.39) | MEN1KMT2ARAB9ANPC1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999479-A | It can be used as the heteroaryl compound of SUMO activating enzyme inhibitors | 米伦纽姆医药公司 | 2017-08-01 | — | — | CN | disclosed |