Tetramethylammonium Ion

Tetramethylammonium Ion

SCHEMBL28147271

C[N+](C)(C)C.O=P([O-])(O)O.[K+].[OH-]

nearest known ligand 0.64

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 1/20 0.64
CA2 P00918 1/20 0.38
BBOX1 O75936 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetramethylammonium Ion SCHEMBL36640 0.93 SLC34A1 (0.61) SLC34A1CA2BBOX1KDM4ECYP2C19
Tetramethylammonium Ion SCHEMBL27796484 0.89 SLC34A1 (0.57) SLC34A1CA2BBOX1KDM4ECYP2C19
Tetramethylammonium Ion SCHEMBL36639 0.85 SLC34A1 (0.50) SLC34A1CA2BBOX1KDM4ECYP2C19
Phosphoric Acid SCHEMBL5993116 0.84
Tetramethylammonium Ion SCHEMBL6320658 0.81 SLC34A1 (0.47) SLC34A1CA2BBOX1KDM4ECYP2C19
Tetramethylammonium Ion SCHEMBL27744546 0.81 SLC34A1 (0.47) SLC34A1CA2BBOX1KDM4ECYP2C19
Tetramethylammonium Ion SCHEMBL28408948 0.81 CA2 (0.46) SLC34A1CA2BBOX1KDM4ELMNA
Phosphoric Acid SCHEMBL301068 0.81
Phosphoric Acid SCHEMBL29020523 0.81
Phosphoric Acid SCHEMBL29273212 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103524711-B Epoxy carboxylate compound, derivative thereof, active energy ray curable resin composition containing them, and cured product thereof 日本化药株式会社 2017-05-17 CN disclosed