Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615205 | 0.86 | HTT (0.56) | CES2LMNAMAPTPOLBHTT | |
| SCHEMBL28487709 | 0.84 | CES2 (0.55) | CES2LMNAMAPTPOLBHTT | |
| SCHEMBL28113932 | 0.83 | MAPT (0.50) | CES2LMNAMAPTPOLBHTT | |
| SCHEMBL4431401 | 0.83 | ALDH1A1 (0.58) | CES2MAPTHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28174395 | 0.81 | CYP19A1 (0.60) | LMNAMAPTPOLBALDH1A1MAPK1 | |
| SCHEMBL29355334 | 0.79 | CES2 (0.75) | CES2LMNAMAPTPOLBHTT | |
| SCHEMBL27497022 | 0.79 | GAA (0.60) | CES2LMNAMAPTPOLBHTT | |
| SCHEMBL5313439 | 0.79 | MAPT (0.60) | CES2LMNAMAPTPOLBHTT | |
| SCHEMBL11010668 | 0.79 | LMNA (0.60) | CES2LMNAMAPTPOLBHTT | |
| SCHEMBL11230405 | 0.79 | CES2 (0.75) | CES2LMNAMAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106795122-B | Nitric Oxide Donor Carnosine Compounds | 尼科斯股份有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-106795122-A | Nitric oxide donor carnosine compounds | 尼科斯科学爱尔兰公司 | 2017-05-31 | — | — | CN | disclosed |