Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760950 | 0.89 | CES2 (0.55) | CES2MAPTLMNAHTTPOLB | |
| SCHEMBL11751170 | 0.85 | ALOX5 (0.57) | CES2MAPTLMNASMN1; SMN2ALOX5 | |
| SCHEMBL27615205 | 0.84 | HTT (0.56) | CES2MAPTLMNAHTTPOLB | |
| SCHEMBL28147378 | 0.84 | CES2 (0.52) | CES2MAPTLMNAHTTPOLB | |
| SCHEMBL28113932 | 0.82 | MAPT (0.50) | CES2MAPTLMNAHTTPOLB | |
| SCHEMBL28174395 | 0.80 | CYP19A1 (0.60) | MAPTLMNAPOLBALDH1A1MAPK1 | |
| SCHEMBL27730499 | 0.79 | MDM2 (0.54) | CES2MAPTLMNASMN1; SMN2ALOX5 | |
| SCHEMBL4697147 | 0.79 | HGFAC (0.67) | CES2MAPTLMNASMN1; SMN2ALOX5 | |
| SCHEMBL9156978 | 0.78 | ALOX5 (0.50) | CES2MAPTLMNASMN1; SMN2ALOX5 | |
| SCHEMBL5313439 | 0.78 | MAPT (0.60) | CES2MAPTLMNAHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010868-B | Method for preparing black reversible thermochromic dye | 华烁科技股份有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-112010868-A | Method for preparing black reversible thermochromic dye | 华烁科技股份有限公司 | 2020-12-01 | — | — | CN | claimed |
| CN-112010868-B | Method for preparing black reversible thermochromic dye | 华烁科技股份有限公司 | 2021-07-27 | — | — | CN | disclosed |
| CN-112010868-A | Method for preparing black reversible thermochromic dye | 华烁科技股份有限公司 | 2020-12-01 | — | — | CN | disclosed |