Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | CCKBR | P32239 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7880670 | 0.90 | LMNA (0.56) | NPC1RAB9ASMN1; SMN2GMNNLMNA | |
| SCHEMBL27319189 | 0.84 | GFER (0.49) | SMN1; SMN2LMNATP53PTGS2MAPK1 | |
| SCHEMBL6707794 | 0.83 | GFER (0.65) | NPC1RAB9ASMN1; SMN2GMNNLMNA | |
| SCHEMBL9429480 | 0.82 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2GMNNLMNA | |
| SCHEMBL9428482 | 0.82 | HTT (0.54) | NPC1RAB9ASMN1; SMN2GMNNLMNA | |
| SCHEMBL27322188 | 0.81 | PTGS2 (0.59) | SMN1; SMN2LMNATP53PTGS2MAPK1 | |
| SCHEMBL9429816 | 0.80 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2GMNNLMNA | |
| SCHEMBL27315061 | 0.80 | CYP1A2 (0.49) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL9428786 | 0.80 | HTT (0.65) | NPC1RAB9ASMN1; SMN2GMNNLMNA | |
| SCHEMBL9429597 | 0.80 | HTT (0.51) | NPC1RAB9ASMN1; SMN2GMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922427-A | Antiviral compounds | 艾丽奥斯生物制药有限公司 | 2018-04-17 | — | — | CN | claimed |
| CN-106999509-A | Therapeutic alliance for treating paramyxovirus | 艾丽奥斯生物制药有限公司 | 2017-08-01 | — | — | CN | claimed |