SCHEMBL28148773

SCHEMBL28148773

CC(=O)C(c1ccc([C]=O)cc1)c1ccc([C@@H](O)CO)cc1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.31
NFKB1 P19838 1/20 0.31
NPC1 O15118 1/20 0.31
FFAR1 O14842 1/20 0.30
F2R P25116 1/20 0.30
ALK Q9UM73 1/20 0.30
SCN9A Q15858 2/20 0.30
ACACB O00763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28148769 1.00 CYP3A4 (0.34) CYP3A4TSHRSMN1; SMN2NFKB1NPC1
SCHEMBL28205264 1.00 CYP3A4 (0.34) CYP3A4TSHRSMN1; SMN2NFKB1NPC1
SCHEMBL28205825 0.88 BRD4 (0.33) NPC1
SCHEMBL28205270 0.88 BRD4 (0.33) NPC1
SCHEMBL28205267 0.86 PTGER2 (0.30)
SCHEMBL28205831 0.85 PRKCA (0.32) FFAR1ACACB
SCHEMBL28844839 0.83 PYGL (0.35) ACACB
SCHEMBL28205269 0.81 NOS3 (0.37) FFAR1ACACB
SCHEMBL28857371 0.81 LMNA (0.47) SMN1; SMN2NPC1
SCHEMBL28149976 0.81 LMNA (0.47) SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105073710-B Novel hydroxamic acid derivative or salt thereof 富山化学工业株式会社 2018-02-16 CN claimed
CN-106794160-A Pharmaceutical composition containing new hydroxamic acid derivative or its salt 富山化学工业株式会社 2017-05-31 CN claimed
CN-106794162-A Method for combined use of novel hydroxamic acid derivatives and antibacterial substances 富山化学工业株式会社 2017-05-31 CN claimed
CN-105073710-B Novel hydroxamic acid derivative or salt thereof 富山化学工业株式会社 2018-02-16 CN disclosed
CN-106794160-A Pharmaceutical composition containing new hydroxamic acid derivative or its salt 富山化学工业株式会社 2017-05-31 CN disclosed
CN-106794162-A Method for combined use of novel hydroxamic acid derivatives and antibacterial substances 富山化学工业株式会社 2017-05-31 CN disclosed
CN-106794162-A Method for combined use of novel hydroxamic acid derivatives and antibacterial substances 富山化学工业株式会社 2017-05-31 CN disclosed