Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
| ▸ | GLS | O94925 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28182184 | 0.81 | CCNT1 (0.31) | CCNT1CCNE1CDK2CDK9 | |
| SCHEMBL1038367 | 0.78 | PRMT6 (0.51) | MAPTPOLBGLS | |
| SCHEMBL22588493 | 0.73 | HTR1A (0.33) | ALDH1A1ATMMGLL | |
| SCHEMBL3298047 | 0.71 | PRMT6 (0.56) | DRD2ALDH1A1MAPTPOLB | |
| SCHEMBL3297964 | 0.71 | PRMT6 (0.53) | DRD2SPHK1ALDH1A1MAPTPOLB | |
| SCHEMBL2362320 | 0.70 | MAPT (0.35) | ALDH1A1MAPT | |
| SCHEMBL3847276 | 0.68 | HTR7 (0.54) | DRD2ALDH1A1 | |
| SCHEMBL671893 | 0.68 | AGXT (0.57) | MTORPIK3CADRD2 | |
| SCHEMBL28918666 | 0.65 | DHFR (0.30) | — | |
| SCHEMBL31385786 | 0.64 | CYP2A6 (0.40) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103917527-B | Dibasic 5 fluoropyrimidine | 拜耳知识产权有限责任公司 | 2017-05-31 | — | — | CN | claimed |
| CN-103917527-B | Dibasic 5 fluoropyrimidine | 拜耳知识产权有限责任公司 | 2017-05-31 | — | — | CN | disclosed |