Hydroxyl Radical

Hydroxyl Radical

SCHEMBL28150321

C=CC(=O)Nc1ccc(C(=O)O)cc1.[OH]

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 11/20 0.66
F13A1 P00488 2/20 0.61
TGM1 P22735 2/20 0.61
LMNA P02545 1/20 0.61
TGM3 Q08188 1/20 0.61
THRB P10828 2/20 0.51
THRA P10827 1/20 0.51
ALDH1A1 P00352 1/20 0.50
KMT2A Q03164 2/20 0.49
MITF O75030 1/20 0.49
MEN1 O00255 1/20 0.49
FFAR1 O14842 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890715 0.98 TGM2 (0.68) TGM2F13A1TGM1LMNATGM3
SCHEMBL21657888 0.88 TGM2 (0.56) TGM2F13A1TGM1LMNATGM3
SCHEMBL439369 0.85 TGM2 (0.79) TGM2F13A1TGM1LMNATGM3
SCHEMBL17327878 0.82 TGM2 (0.63) TGM2F13A1TGM1LMNATGM3
SCHEMBL24510652 0.82 ALDH1A1 (0.52) TGM2F13A1TGM1LMNATGM3
SCHEMBL29684447 0.81 TGM2 (0.72) TGM2F13A1TGM1LMNATGM3
SCHEMBL39036 0.81 TGM2 (0.72) TGM2F13A1TGM1LMNATGM3
SCHEMBL3633294 0.81 TGM2 (0.51) TGM2F13A1TGM1LMNATGM3
SCHEMBL6357758 0.81 TGM2 (0.61) TGM2F13A1TGM1LMNATGM3
SCHEMBL7470743 0.81 TGM2 (0.67) TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715747-A Cured film forms composition 日产化学株式会社 2019-05-03 CN disclosed
CN-104603650-B It is orientated manufacture method, orientation material, the manufacture method of phase difference material and the phase difference material of material 日产化学工业株式会社 2017-06-06 CN disclosed