Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890715 | 0.84 | TGM2 (0.68) | ALDH1A1MEN1KMT2AMITFFFAR1 | |
| Hydroxyl Radical SCHEMBL28150321 | 0.82 | TGM2 (0.66) | ALDH1A1MEN1KMT2AMITFFFAR1 | |
| SCHEMBL877744 | 0.78 | HCAR3 (0.58) | ALDH1A1MEN1KMT2AMITFFFAR1 | |
| SCHEMBL22183966 | 0.78 | KDM4E (0.40) | ALDH1A1MEN1KMT2ATGM2PKM | |
| SCHEMBL23336405 | 0.78 | TGM2 (0.46) | ALDH1A1MEN1KMT2ATP53TGM2 | |
| SCHEMBL15213831 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMITFFFAR1 | |
| SCHEMBL1457833 | 0.77 | HCAR3 (0.57) | ALDH1A1MEN1KMT2AMITFFFAR1 | |
| Hydrochloric Acid SCHEMBL9551144 | 0.77 | HCAR3 (0.57) | ALDH1A1MEN1KMT2AMITFFFAR1 | |
| SCHEMBL8476851 | 0.77 | KMT2A (0.60) | ALDH1A1MEN1KMT2AMITFFFAR1 | |
| SCHEMBL4745756 | 0.76 | EPHX2 (0.71) | ALDH1A1MEN1KMT2AMITFFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022126000-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2022-06-16 | — | — | WO | disclosed |