Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29191209 | 0.81 | GPR119 (0.42) | GPR119PTPN1ALDH1A1MAPT | |
| SCHEMBL20033881 | 0.79 | BCHE (0.38) | GPR119PTPN2PTPN1PTPN6BCHE | |
| SCHEMBL7528678 | 0.77 | ESR2 (0.40) | GPR119PTPN2PTPN1PTPN6BCHE | |
| SCHEMBL11911366 | 0.77 | GPR119 (0.39) | GPR119PTPN2PTPN1PTPN6BCHE | |
| SCHEMBL28446456 | 0.77 | HTT (0.38) | PTPN2PTPN1PTPN6ALDH1A1MEN1 | |
| SCHEMBL12593934 | 0.76 | NR1H2 (0.41) | GPR119BCHEMEN1KMT2AL3MBTL1 | |
| SCHEMBL1018306 | 0.76 | BCHE (0.38) | GPR119PTPN2PTPN1PTPN6BCHE | |
| SCHEMBL28581988 | 0.76 | BCHE (0.38) | GPR119BCHEALDH1A1MEN1KMT2A | |
| SCHEMBL7023132 | 0.75 | NR1H2 (0.41) | BCHEALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19638080 | 0.75 | GPR119 (0.38) | GPR119BCHEALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486876-A | Compounds as inhibitors of Akt kinase | 正大天晴药业集团股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116194452-A | Compounds as inhibitors of Akt kinase | 正大天晴药业集团股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-106630205-A | Anti-scale inhibitor for treating industrial circulating water | 安徽省蓝天能源环保科技有限公司 | 2017-05-10 | — | — | CN | disclosed |