Lisadimate

Lisadimate

SCHEMBL28150985

Nc1ccc(C(=O)OCC(O)CO)cc1.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
ADRB2 P07550 9/20 0.56
ADRB1 P08588 9/20 0.56
ADRB3 P13945 9/20 0.56
PRKCA P17252 1/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
LMNA P02545 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
MAOA P21397 1/20 0.46
SLC1A5 Q15758 1/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lisadimate SCHEMBL62520 0.90 ADRB2 (0.66) ALDH1A1ADRB2ADRB1ADRB3NPC1
SCHEMBL1866113 0.87 ALDH1A1 (0.70) ALDH1A1ADRB2ADRB1ADRB3PRKCA
SCHEMBL1866116 0.87 ALDH1A1 (0.70) ALDH1A1ADRB2ADRB1ADRB3PRKCA
SCHEMBL3391 0.87 ALDH1A1 (0.70) ALDH1A1ADRB2ADRB1ADRB3PRKCA
SCHEMBL20515564 0.85 ALDH1A1 (0.68) ALDH1A1ADRB2ADRB1ADRB3PRKCA
Lisadimate SCHEMBL7263680 0.83 LMNA (0.71) ALDH1A1ADRB2ADRB1ADRB3NPC1
Benzoic Acid SCHEMBL7688676 0.82 ALDH1A1 (0.64) ALDH1A1ADRB2ADRB1ADRB3PRKCA
Benzoic Acid SCHEMBL9956241 0.82 ALDH1A1 (0.64) ALDH1A1ADRB2ADRB1ADRB3PRKCA
Benzoic Acid SCHEMBL28388934 0.82 ALDH1A1 (0.64) ALDH1A1ADRB2ADRB1ADRB3PRKCA
Acetic Acid SCHEMBL28698833 0.82 ALDH1A1 (0.64) ALDH1A1ADRB2ADRB1ADRB3PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107072902-A The purposes of cosmetic composition comprising 10 hydroxy stearic acids 帝斯曼知识产权资产管理有限公司 2017-08-18 CN disclosed