Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.52 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.52 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202951 | 0.87 | CYP1A2 (0.60) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL27961047 | 0.86 | CYP1A2 (0.68) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL5255224 | 0.85 | GPR35 (0.53) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL5333075 | 0.84 | CYP1A2 (0.66) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL8652551 | 0.84 | CYP1A2 (0.57) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL10890268 | 0.82 | CYP1A2 (0.64) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL188306 | 0.82 | CYP1A2 (0.64) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL29638033 | 0.82 | CYP1A2 (0.64) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL7665273 | 0.82 | CYP1A2 (0.64) | CYP1A2TDP1ALDH1A1TSHRGPR35 | |
| SCHEMBL10891708 | 0.82 | CYP1A2 (0.64) | CYP1A2TDP1ALDH1A1TSHRGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10577459-B2 | Aliphatic poly(ester)s with thiol pendant groups | WISTRAND, Anna (SE) | 2020-03-03 | — | — | US | claimed |
| US-20180305495-A1 | ALIPHATIC POLY(ESTER)S WITH THIOL PENDANT GROUPS | PAPPALARDO, Daniela (IT) | 2018-10-25 | — | — | US | claimed |
| EP-3362500-A1 | ALIPHATIC POLY(ESTER)S WITH THIOL PENDANT GROUPS | Novus Scientific AB (SE) | 2018-08-22 | — | — | EP | claimed |
| WO-2017064291-A1 | ALIPHATIC POLY(ESTER)S WITH THIOL PENDANT GROUPS | NOVUS SCIENTIFIC AB (SE) | 2017-04-20 | — | — | WO | claimed |
| EP-1626952-B1 | MULTIFUNCTIONAL REAGENT FOR THE SYNTHESIS OF THIOL MODIFIED OLIGOMERS | FRIZ BIOCHEM GES FÜR BIOANALYTIK MBH (DE) | 2014-06-04 | — | — | EP | claimed |
| EP-1594835-A4 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS INC (US) | 2007-05-02 | — | — | EP | claimed |
| US-20060173199-A1 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | HONG BORCHERNG | 2006-08-03 | — | — | US | claimed |
| EP-1626952-A2 | MULTIFUNCTIONAL REAGENT FOR THE SYNTHESIS OF THIOL MODIFIED OLIGOMERS | FRIZ Biochem Gesellschaft für Bioanalytik mbH (DE) | 2006-02-22 | — | — | EP | claimed |
| EP-1594835-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | Auspex Pharmaceuticals, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| US-20050153291-A1 | Multifunctional reagent for the synthesis of thiol modified oligomers | FRIZ BIOCHEM GESELLSCHAFT FUR BIOANALYTIK MBH (DE) | 2005-07-14 | — | — | US | claimed |
| WO-2004064745-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2004-08-05 | — | — | WO | claimed |
| WO-2003055852-A2 | MULTIFUNCTIONAL REAGENT FOR THE SYNTHESIS OF THIOL MODIFIED OLIGOMERS | FRIZ BIOCHEM GMBH (DE) | 2003-07-10 | — | — | WO | claimed |
| US-6359144-B1 | BIOSYNTHESIS; SCREENING | LION BIOSCIENCE AG (DE) | 2002-03-19 | — | — | US | claimed |
| WO-1998034113-A1 | COMBINATORIAL LIBRARIES OF BICYCLIC GUANIDINE DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| US-5786448-A | FOR SCREENING, SYNTHESIZING PEPTIDE DERIVATIVES | TREGA BIOSCIENCES, INC. (US) | 1998-07-28 | — | — | US | claimed |
| WO-1998019693-A1 | COMBINATORIAL LIBRARIES OF CYCLIC UREA AND CYCLIC THIOUREA DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-05-14 | — | — | WO | claimed |
| US-20240218014-A1 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-04 | — | — | US | disclosed |
| WO-2024133853-A1 | BIS-ESTER AND AMIDE CATIONIC LIPIDS | SANOFI (FR) | 2024-06-27 | — | — | WO | disclosed |
| EP-0035046-A1 | Novel tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-09 | — | — | EP | disclosed |
| US-3971825-A | (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS | SANKYO COMPANY LIMITED (JA) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240218014-A1 | SYNTHESIS OF A CYCLIC PEPTIDE | VIP, QPCT, PTMS | CYP1A2 4134/4885TDP1 3845/4885ALDH1A1 4766/4885 |
| US-20050153291-A1 | Multifunctional reagent for the synthesis of thiol modified oligomers | CBR3, NOX3, CBR1 | CYP1A2 1761/4885TDP1 4199/4885ALDH1A1 3696/4885 |
| US-10577459-B2 | Aliphatic poly(ester)s with thiol pendant groups | PARG, TST, CBS | CYP1A2 2443/4885TDP1 2088/4885ALDH1A1 431/4885 |
| US-20180305495-A1 | ALIPHATIC POLY(ESTER)S WITH THIOL PENDANT GROUPS | PARG, TST, CBS | CYP1A2 2443/4885TDP1 2088/4885ALDH1A1 431/4885 |
| US-20060173199-A1 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | LSS, DHPS, CYP51A1 | CYP1A2 91/4885TDP1 2430/4885ALDH1A1 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.