SCHEMBL28153591

SCHEMBL28153591

Clc1cc(Cl)ncn1.[NaH].[NaH]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NPC1 O15118 1/20 0.36
RECQL P46063 1/20 0.33
LOX P28300 1/20 0.33
LOXL3 P58215 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
CDC7 O00311 1/20 0.33
DAPK3 O43293 1/20 0.33
MAP4K4 O95819 1/20 0.33
PIM1 P11309 1/20 0.33
PRKACA P17612 1/20 0.33
FLT3 P36888 1/20 0.33
CDK8 P49336 1/20 0.33
CLK2 P49760 1/20 0.33
GSK3B P49841 1/20 0.33
CDK7 P50613 1/20 0.33
CDK9 P50750 1/20 0.33
PRKX P51817 1/20 0.33
CDK5 Q00535 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31051471 0.96
Methylene Chloride SCHEMBL27947432 0.87 MEN1 (0.38) MEN1KMT2ANPC1RECQLLOX
Acetaldehyde SCHEMBL28232456 0.80 NPC1 (0.35) MEN1KMT2ANPC1
SCHEMBL29136970 0.80 KMO (0.44) MEN1KMT2ANPC1LOXLOXL3
Isopropyl Alcohol SCHEMBL28207243 0.80 NPC1 (0.35) MEN1KMT2ANPC1RECQL
Chlorobenzene SCHEMBL27930649 0.78 TSHR (0.55) MEN1KMT2ANPC1MAP4K4CDK7
Bicarbonate SCHEMBL28202844 0.78 KMO (0.33) MEN1KMT2ANPC1RECQL
SCHEMBL858924 0.76
SCHEMBL6128470 0.76
SCHEMBL1851665 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106885866-B A kind of constituent analysis test method of the 4,6- dihydroxy-pyrimidine reaction solutions of bipolar film process 重庆紫光国际化工有限责任公司 2018-06-26 CN disclosed
CN-106885866-A A kind of constituent analysis method of testing of 4,6 dihydroxy-pyrimidine reaction solutions of bipolar film process 重庆紫光国际化工有限责任公司 2017-06-23 CN disclosed