Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31051471 | 0.83 | — | — | |
| SCHEMBL39924 | 0.83 | — | — | |
| SCHEMBL1661171 | 0.81 | NPC1 (0.32) | NPC1MEN1KMT2A | |
| SCHEMBL28153591 | 0.80 | MEN1 (0.40) | NPC1MEN1KMT2ARECQL | |
| SCHEMBL29183352 | 0.77 | NOS2 (0.41) | — | |
| SCHEMBL29183349 | 0.77 | NOS2 (0.41) | — | |
| SCHEMBL30741556 | 0.77 | NOS2 (0.41) | — | |
| SCHEMBL857697 | 0.75 | NPC1 (0.33) | NPC1MEN1KMT2AOGA | |
| Methylene Chloride SCHEMBL27947432 | 0.75 | MEN1 (0.38) | NPC1MEN1KMT2ARECQL | |
| SCHEMBL22163937 | 0.74 | MEN1 (0.34) | NPC1MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923021-B | It is suitable for the heteroaryl compound of E1 activating enzyme inhibitors | 米伦纽姆医药公司 | 2018-03-30 | — | — | CN | disclosed |