Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15529065 | 0.95 | ACACB (0.46) | ACACBADAMTS5HSD11B1SPRNAMPT | |
| SCHEMBL28154378 | 0.86 | ACACB (0.46) | ACACBADAMTS5HSD11B1DPP4DPP8 | |
| SCHEMBL28154398 | 0.85 | NAMPT (0.52) | ACACBHSD11B1DPP4DPP8DPP9 | |
| SCHEMBL15529439 | 0.85 | ADAMTS5 (0.43) | ACACBADAMTS5HSD11B1SPRNAMPT | |
| SCHEMBL28154384 | 0.85 | PDE10A (0.46) | ACACBADAMTS5HSD11B1SPRNAMPT | |
| SCHEMBL28154404 | 0.85 | CYP3A4 (0.48) | ACACBADAMTS5HSD11B1SPRNAMPT | |
| SCHEMBL15529814 | 0.85 | NAMPT (0.53) | NAMPT | |
| SCHEMBL28155324 | 0.85 | ACACB (0.47) | ACACBADAMTS5HSD11B1SPRNAMPT | |
| SCHEMBL28155438 | 0.84 | ACACB (0.46) | ACACBHSD11B1DPP4DPP8DPP9 | |
| SCHEMBL28154386 | 0.83 | HSD11B1 (0.47) | ACACBADAMTS5HSD11B1SPRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104684906-B | Nampt inhibitor | 艾伯维公司 | 2017-06-09 | — | — | CN | claimed |