SCHEMBL28155264

SCHEMBL28155264

Nc1c(OC=O)ccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.63
MAOA P21397 3/20 0.57
MAOB P27338 1/20 0.57
MEN1 O00255 9/20 0.54
KMT2A Q03164 9/20 0.54
ALDH1A1 P00352 8/20 0.54
MAPT P10636 8/20 0.54
MAPK1 P28482 7/20 0.54
RAB9A P51151 5/20 0.54
POLB P06746 5/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
NPC1 O15118 4/20 0.54
TDP1 Q9NUW8 4/20 0.54
THRB P10828 3/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
CYP3A4 P08684 3/20 0.54
LMNA P02545 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
MCL1 Q07820 2/20 0.54
TSHR P16473 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9751849 0.80 RAB9A (0.68) ADORA2AMAOAMAOBMEN1KMT2A
SCHEMBL5014653 0.80 KCNA3 (0.51) ADORA2AMAOAMAOBMEN1KMT2A
SCHEMBL4397430 0.77 ADORA2A (0.68) ADORA2AMAOAMAOBMEN1KMT2A
SCHEMBL8777916 0.77 ADORA2A (0.63) ADORA2AMAOAMAOBMEN1KMT2A
SCHEMBL27886984 0.77 ADORA2A (0.63) ADORA2AMAOAMAOBMEN1KMT2A
SCHEMBL9509808 0.76 ADORA2A (0.61) ADORA2AMAOAMAOBMEN1KMT2A
SCHEMBL17718229 0.76 KMT2A (0.45) ADORA2AMEN1KMT2AALDH1A1MAPT
SCHEMBL8777904 0.75 ADORA2A (0.60) ADORA2AMAOAMAOBMEN1KMT2A
SCHEMBL6635611 0.75 MAOA (0.62) ADORA2AMAOAMAOBMEN1KMT2A
Methoxymethane SCHEMBL11741879 0.75 MAOA (0.86) ADORA2AMAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106824265-A Spray aerogel drop haze cold clouds and preparation method thereof in a kind of high-altitude 徐州工程学院 2017-06-13 CN claimed
CN-106824265-A Spray aerogel drop haze cold clouds and preparation method thereof in a kind of high-altitude 徐州工程学院 2017-06-13 CN disclosed