3-Methoxyphenylacetonitrile

3-Methoxyphenylacetonitrile

SCHEMBL28155308

COc1ccc(CC#N)cc1.c1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.58
LTA4H P09960 2/20 0.55
PBRM1 Q86U86 1/20 0.49
IDO1 P14902 3/20 0.48
FLT3 P36888 1/20 0.48
CA4 P22748 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
ALDH1A1 P00352 2/20 0.46
SIGMAR1 Q99720 1/20 0.46
GAA P10253 1/20 0.46
AGXT P21549 2/20 0.45
TAAR1 Q96RJ0 1/20 0.45
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
MIF P14174 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Methoxyphenylacetonitrile SCHEMBL7135147 0.96 LTA4H (0.62) PKMLTA4HPBRM1IDO1FLT3
3-Methoxyphenylacetonitrile SCHEMBL103029 0.96 PKM (0.61) PKMLTA4HIDO1FLT3CA12
3-Methoxyphenylacetonitrile SCHEMBL27728444 0.94 PKM (0.59) PKMLTA4HIDO1FLT3CA12
3-Methoxyphenylacetonitrile SCHEMBL29253102 0.94 PKM (0.59) PKMLTA4HIDO1FLT3CA12
SCHEMBL5004118 0.90 FLT3 (0.57) PKMLTA4HIDO1FLT3CA12
SCHEMBL8992958 0.90 LTA4H (0.59) PKMLTA4HIDO1FLT3CA12
SCHEMBL20879574 0.86 ACHE (0.50) PKMLTA4HIDO1FLT3ALDH1A1
SCHEMBL6933353 0.85 PKM (0.52) PKMLTA4HIDO1FLT3CA12
SCHEMBL3520397 0.85 APP (0.61) PKMIDO1ALDH1A1AGXTMAOB
3-Methoxyphenylacetonitrile SCHEMBL754486 0.82 PKM (0.49) PKMLTA4HIDO1FLT3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447582-B Tetraphernl pyrazine small molecule derivative, tetraphernl pyrazine polymer and gathering induced luminescence material 浙江大学 2017-07-07 CN disclosed