Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27860426 | 0.80 | TAAR1 (0.47) | POLBTDP1HPGDALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL28161994 | 0.78 | TAAR1 (0.45) | POLBTDP1HPGDALDH1A1HTT | |
| SCHEMBL4134981 | 0.74 | CYP2C19 (0.47) | POLBTDP1HPGDALDH1A1TAAR1 | |
| SCHEMBL25374097 | 0.71 | RAB9A (0.46) | POLBTDP1HPGDALDH1A1TAAR1 | |
| SCHEMBL8083549 | 0.70 | SRC (0.47) | POLBTDP1HPGDALDH1A1CYP2C19 | |
| SCHEMBL518265 | 0.70 | CYP3A4 (0.68) | HPGDALDH1A1GAAHTTMAPT | |
| SCHEMBL755028 | 0.70 | CYP3A4 (0.68) | HPGDALDH1A1GAAHTTMAPT | |
| SCHEMBL752826 | 0.70 | HTT (0.66) | HPGDALDH1A1GAAHTTMAPT | |
| SCHEMBL27455836 | 0.69 | TSHR (0.71) | POLBTDP1HPGDALDH1A1GAA | |
| SCHEMBL5570426 | 0.69 | ALDH1A1 (0.64) | ALDH1A1GAAHTTMAPTALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294776-B | Method for preparing aryl phosphine oxide derivative | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-109678901-B | Synthesis method of tri-substituted phosphine oxide compound | 信阳师范学院 | 2021-05-28 | — | — | CN | disclosed |
| CN-110294776-A | A method of preparing aryl oxide phosphine-derivatives | 苏州大学 | 2019-10-01 | — | — | CN | disclosed |
| CN-109678901-A | A kind of three replace the synthetic method of phosphine oxide compound | 信阳师范学院 | 2019-04-26 | — | — | CN | disclosed |
| CN-107021982-A | The synthetic method of three substitution phosphine oxide compounds or three two phosphine oxide compounds of substitution | 温州大学 | 2017-08-08 | — | — | CN | disclosed |