Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30389716 | 1.00 | LMNA (0.44) | LMNAL3MBTL1MAPTXBP1G6PC1 | |
| SCHEMBL29229485 | 0.81 | CHRM5 (0.53) | MAPTALDH1A1MAPK1KDM4EGRIN2D | |
| SCHEMBL27991294 | 0.78 | CHRM5 (0.38) | LMNAL3MBTL1MAPTG6PC1ACHE | |
| SCHEMBL28186169 | 0.77 | MAOB (0.45) | LMNAMAPTALDH1A1MAPK1KDM4E | |
| SCHEMBL28186173 | 0.77 | MAOB (0.45) | LMNAMAPTALDH1A1MAPK1KDM4E | |
| SCHEMBL27804939 | 0.74 | GPR3 (0.37) | ACHEALDH1A1BCHEGPR3HTR2A | |
| SCHEMBL28355026 | 0.73 | GPR3 (0.34) | LMNAACHEALDH1A1TSHRMAPK1 | |
| SCHEMBL28355025 | 0.73 | GPR3 (0.34) | LMNAACHEALDH1A1TSHRMAPK1 | |
| Ammonia Solution, Strong SCHEMBL28186930 | 0.72 | GPR3 (0.33) | LMNAACHEALDH1A1TSHRMAPK1 | |
| SCHEMBL2042756 | 0.71 | ALDH1A1 (0.46) | LMNAL3MBTL1MAPTXBP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109136974-A | One kind (sp containing C2)-N key compound preparation method | 中国科学院上海有机化学研究所 | 2019-01-04 | — | — | CN | disclosed |
| CN-107531737-A | Synthesis of desosamine | 哈佛大学的校长及成员们 | 2018-01-02 | — | — | CN | disclosed |
| CN-106998685-A | 14-membered ketolides and methods of making and using the same | 哈佛大学的校长及成员们 | 2017-08-01 | — | — | CN | disclosed |