Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28186173 | 1.00 | MAOB (0.45) | MAOBGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL30389716 | 0.77 | LMNA (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL28158482 | 0.77 | LMNA (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11778542 | 0.69 | GRIN2D (0.67) | MAOBGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11326545 | 0.69 | GRIN2D (0.67) | MAOBGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27804939 | 0.69 | GPR3 (0.37) | ALDH1A1CYP1A2POLBMEN1KMT2A | |
| SCHEMBL24407985 | 0.68 | RAB9A (0.50) | MAOBGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9842358 | 0.68 | RAB9A (0.50) | MAOBGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7026081 | 0.68 | RAB9A (0.50) | MAOBGAAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7026078 | 0.68 | RAB9A (0.50) | MAOBGAAGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107473982-A | Hold position substitution high allyl amine derivative and its production and use | 四川大学 | 2017-12-15 | — | — | CN | disclosed |