Benzene

Benzene

SCHEMBL28159586

O=C(C(F)(F)F)C(F)(F)F.c1ccccc1

nearest known ligand 0.46

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.46
CA2 P00918 2/20 0.35
CES2 O00748 1/20 0.33
FAAH O00519 3/20 0.32
HDAC6 Q9UBN7 2/20 0.32
PTPN1 P18031 1/20 0.32
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CPA1 P15085 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL6668489 0.92 CA2 (0.39) CES1CA2CES2ALDH1A1L3MBTL1
Hydrogen Peroxide SCHEMBL6668485 0.92 CA2 (0.39) CES1CA2CES2ALDH1A1L3MBTL1
SCHEMBL27892503 0.88 CA2 (0.41) CES1CA2CES2FAAHALDH1A1
SCHEMBL344 0.88 CA2 (0.41) CES1CA2CES2FAAHALDH1A1
Trifluoroacetic Acid SCHEMBL9724655 0.85 ALDH1A1 (0.38) CES1CA2CES2ALDH1A1L3MBTL1
Fluoride SCHEMBL1594462 0.84 CA2 (0.39) CES1CA2CES2ALDH1A1
SCHEMBL11799381 0.84 CA2 (0.39) CES1CA2CES2ALDH1A1
SCHEMBL11800353 0.84 CA2 (0.39) CES1CA2CES2ALDH1A1
SCHEMBL7149277 0.84 CA2 (0.39) CES1CA2CES2ALDH1A1
SCHEMBL9473581 0.84 CA2 (0.39) CES1CA2CES2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104548146-B Magnetic resonance developer of a kind of dendritic macromole fluorine 19 and its preparation method and application 武汉大学 2017-06-16 CN disclosed