Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788443 | 0.89 | REN (0.37) | REN | |
| SCHEMBL2790585 | 0.82 | REN (0.38) | REN | |
| SCHEMBL2790479 | 0.76 | ALDH1A1 (0.31) | REN | |
| SCHEMBL2790483 | 0.76 | ALDH1A1 (0.31) | REN | |
| SCHEMBL7899334 | 0.73 | CFD (0.35) | — | |
| SCHEMBL2789055 | 0.73 | CFD (0.33) | — | |
| SCHEMBL2789237 | 0.73 | CNR2 (0.37) | REN | |
| SCHEMBL7897742 | 0.72 | CFD (0.34) | — | |
| SCHEMBL2788359 | 0.72 | CFD (0.33) | — | |
| SCHEMBL2792686 | 0.71 | DPP4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |