SCHEMBL2816101

SCHEMBL2816101

CN[C@H](CCSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 18/20 0.51
DNMT1 P26358 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2816104 1.00 KIF11 (0.51) KIF11DNMT1
SCHEMBL27558321 1.00 KIF11 (0.51) KIF11DNMT1
SCHEMBL2815492 0.90 KIF11 (0.59) KIF11DNMT1
SCHEMBL2815491 0.90 KIF11 (0.59) KIF11DNMT1
SCHEMBL20202837 0.84 KIF11 (0.56) KIF11DNMT1
SCHEMBL30408374 0.84 KIF11 (0.56) KIF11DNMT1
SCHEMBL4410619 0.84 KIF11 (0.56) KIF11DNMT1
SCHEMBL27452677 0.83 KIF11 (0.45) KIF11DNMT1
SCHEMBL4462198 0.80 KIF11 (0.47) KIF11DNMT1
SCHEMBL4462208 0.80 KIF11 (0.47) KIF11DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7659364-B2 N-methyl-homocysteines and their use as well as process for their production CIS BIO INTERNATIONAL (FR) 2010-02-09 US disclosed
EP-1444194-B1 N-METHYL-HOMOCYSTINES, USE THEREOF AND METHOD FOR THE PRODUCTION THEREOF CIS BIO INT (FR) 2009-12-09 EP disclosed
CN-1304363-C N-methyl-homocysteines and their use as well as process for their production CIS BIOLOGY INTERNAT CO (FR) 2007-03-14 CN disclosed
CN-1589257-A N-methyl-homocysteine and application and preparation method thereof SCHERING AG (DE) 2005-03-02 CN disclosed
EP-1444194-A1 N-METHYL-HOMOCYSTINES, USE THEREOF AND METHOD FOR THE PRODUCTION THEREOF SCHERING AKTIENGESELLSCHAFT (DE) 2004-08-11 EP disclosed
US-20030120032-A1 N-methyl-homocysteines and their use as well as process for their production SCHERING AG (DE) 2003-06-26 US disclosed
WO-2003042163-A1 N-METHYL-HOMOCYSTINES, USE THEREOF AND METHOD FOR THE PRODUCTION THEREOF SCHERING AKTIENGESELLSCHAFT (DE) 2003-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120032-A1 N-methyl-homocysteines and their use as well as process for their production BHMT, BHMT2, AHCY KIF11 4731/4885DNMT1 55/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.