SCHEMBL28162191

SCHEMBL28162191

CCC[Si](OC)(OC)N1CCCCC1CC

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.32
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
PSEN1 P49768 1/20 0.30
PSEN2 P49810 1/20 0.30
APH1B Q8WW43 1/20 0.30
NCSTN Q92542 1/20 0.30
APH1A Q96BI3 1/20 0.30
PSENEN Q9NZ42 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13835821 0.90 SMN1; SMN2 (0.33) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2
SCHEMBL7708208 0.88 CHRNB2 (0.37) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2
SCHEMBL6065996 0.84 MAPK1 (0.32) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2
SCHEMBL137670 0.83 KMT2A (0.32) MAPK1ALDH1A1KMT2AHTT
SCHEMBL4578056 0.81 TSHR (0.33) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2
SCHEMBL137671 0.77 MEN1 (0.32) MAPK1ALDH1A1KMT2A
SCHEMBL301755 0.75 MEN1 (0.30) KMT2ATSHR
SCHEMBL560708 0.73 MAPK1 (0.34) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2
SCHEMBL8376783 0.72 KMT2A (0.39) MAPK1ALDH1A1KMT2AKDM4ETSHR
SCHEMBL569945 0.72 MAPK1 (0.32) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104995220-B Terpolymer based on propylene 巴塞尔聚烯烃意大利有限公司 2017-08-15 CN disclosed