SCHEMBL560708

SCHEMBL560708

CCC1CCCCN1[Si](OC)(OC)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KMT2A Q03164 1/20 0.33
FKBP1A P62942 1/20 0.32
KDM4E B2RXH2 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
ATM Q13315 1/20 0.31
PSEN1 P49768 1/20 0.30
PSEN2 P49810 1/20 0.30
APH1B Q8WW43 1/20 0.30
NCSTN Q92542 1/20 0.30
APH1A Q96BI3 1/20 0.30
PSENEN Q9NZ42 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL569945 0.84 MAPK1 (0.32) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2
SCHEMBL569946 0.84 MAPK1 (0.32) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2
SCHEMBL137669 0.79 MEN1 (0.32) MAPK1KMT2A
SCHEMBL28638470 0.79 MAPK1 (0.37) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2
SCHEMBL7609332 0.77 ALDH1A1 (0.30) ALDH1A1SMN1; SMN2KMT2A
SCHEMBL28162191 0.73 MAPK1 (0.34) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2
SCHEMBL8376783 0.72 KMT2A (0.39) MAPK1ALDH1A1KMT2AKDM4ETSHR
SCHEMBL303064 0.71 RIPK1 (0.30)
SCHEMBL13835821 0.71 SMN1; SMN2 (0.33) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2
SCHEMBL4578056 0.71 TSHR (0.33) MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024107076-A1 PROCATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PREPARATION THEREOF PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (PJSC "SIBUR HOLDING") (RU) 2024-05-23 WO claimed
WO-2024107086-A1 PROCATALYST FOR OLEFIN POLYMERIZATION AND USE THEREOF PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (PJSC "SIBUR HOLDING") (RU) 2024-05-23 WO claimed
US-10125200-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-11-13 US claimed
EP-1165633-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA (IT) 2004-07-14 EP claimed
US-6716939-B2 COMPRISING TITANIUM, MAGNESIUM, HALOGEN AND AN ELECTRON DONOR COMPOUND SELECTED FROM ESTERS OF SUBSTITUTED SUCCINIC ACIDS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-04-06 US claimed
EP-0994905-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA (IT) 2004-01-21 EP claimed
US-20020183575-A1 Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-12-05 US claimed
US-6395670-B1 COORDINATION CATALYSTS BASELL TECHNOLOGY COMPANY BV (NL) 2002-05-28 US claimed
EP-1165633-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2002-01-02 EP claimed
WO-2001057099-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-08-09 WO claimed
US-12637556-B2 Ultrasoft polyolefin composition BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2026-05-26 US disclosed
US-12600845-B2 Propylene polymer composition BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2026-04-14 US disclosed
EP-4720138-A1 PROCESS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2026-04-08 EP disclosed
EP-4720139-A1 PROCESS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2026-04-08 EP disclosed
EP-4713375-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2026-03-25 EP disclosed
US-6395670-B1 COORDINATION CATALYSTS BASELL TECHNOLOGY COMPANY BV (NL) 2002-05-28 US disclosed
EP-1165633-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2002-01-02 EP disclosed
WO-2001057099-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-08-09 WO disclosed
EP-0994905-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Montell Technology Company bv (NL) 2000-04-26 EP disclosed
WO-1999057160-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1999-11-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600845-B2 Propylene polymer composition LBR, FGR, MSH2 MAPK1 3351/4885ALDH1A1 4628/4885CRHBP 680/4885
US-12637556-B2 Ultrasoft polyolefin composition LBR, CHRND, FPR1 MAPK1 3129/4885ALDH1A1 3966/4885CRHBP 659/4885
US-20020183575-A1 Components and catalysts for the polymerization of olefins SCO2, ECI1, MT-CO2 MAPK1 2086/4885ALDH1A1 3479/4885CRHBP 846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.