Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835821 | 0.88 | SMN1; SMN2 (0.33) | MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL7708208 | 0.85 | CHRNB2 (0.37) | MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL28162191 | 0.84 | MAPK1 (0.34) | MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL137670 | 0.81 | KMT2A (0.32) | MAPK1ALDH1A1KMT2A | |
| SCHEMBL4578056 | 0.76 | TSHR (0.33) | MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL137671 | 0.75 | MEN1 (0.32) | MAPK1ALDH1A1KMT2A | |
| SCHEMBL28638470 | 0.74 | MAPK1 (0.37) | MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL560708 | 0.69 | MAPK1 (0.34) | MAPK1ALDH1A1CRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL8376783 | 0.68 | KMT2A (0.39) | MAPK1ALDH1A1KMT2A | |
| SCHEMBL560611 | 0.67 | MAPK1 (0.31) | MAPK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6998458-B2 | Butene-1 (co)polymers and process for their preparation | BASELL POLIOLEFINE ITALIS S.P.A. (IT) | 2006-02-14 | — | — | US | disclosed |