Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835821 | 0.94 | SMN1; SMN2 (0.33) | CHRNB2CHRNA7CHRNA4SMN1; SMN2HSD17B10 | |
| SCHEMBL28162191 | 0.88 | MAPK1 (0.34) | SMN1; SMN2TSHRKDM4EMAPK1ALDH1A1 | |
| SCHEMBL6065996 | 0.85 | MAPK1 (0.32) | SMN1; SMN2MAPK1ALDH1A1CRHBPCRHR2 | |
| SCHEMBL137670 | 0.78 | KMT2A (0.32) | MAPK1ALDH1A1 | |
| SCHEMBL4578056 | 0.76 | TSHR (0.33) | SMN1; SMN2NPSR1TSHRKDM4EMAPK1 | |
| SCHEMBL9279208 | 0.74 | LMNA (0.34) | TSHR | |
| SCHEMBL28638470 | 0.74 | MAPK1 (0.37) | CHRNB2CHRNA7CHRNA4SMN1; SMN2NPSR1 | |
| SCHEMBL9282463 | 0.73 | L3MBTL1 (0.34) | KDM4E | |
| SCHEMBL137671 | 0.72 | MEN1 (0.32) | MAPK1ALDH1A1 | |
| SCHEMBL560708 | 0.69 | MAPK1 (0.34) | SMN1; SMN2TSHRKDM4EMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395670-B1 | COORDINATION CATALYSTS | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-05-28 | — | — | US | claimed |
| CN-109983070-B | Heterophasic propylene copolymer | 巴塞尔聚烯烃意大利有限公司 | 2020-04-03 | — | — | CN | disclosed |