Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815726 | 0.89 | FBP1 (0.46) | FBP1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL2812983 | 0.84 | FBP1 (0.47) | FBP1ALDH1A1GAAL3MBTL1KMT2A | |
| SCHEMBL3991445 | 0.84 | FBP1 (0.47) | FBP1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL2812988 | 0.82 | SMN1; SMN2 (0.45) | FBP1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL2817159 | 0.82 | FBP1 (0.48) | FBP1RAB9AMAPTGAATP53 | |
| SCHEMBL2818263 | 0.82 | RAB9A (0.39) | RAB9AGBA1MAPTALDH1A1GAA | |
| SCHEMBL2816853 | 0.80 | FBP1 (0.43) | FBP1MAPTALDH1A1GAALMNA | |
| SCHEMBL2814384 | 0.80 | FBP1 (0.46) | FBP1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL2815885 | 0.80 | FBP1 (0.42) | FBP1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL2816885 | 0.80 | FBP1 (0.47) | FBP1NTRK1NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249132-A1 | IMIDAZOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-09-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249132-A1 | IMIDAZOLE DERIVATIVES | SDHA, SDHB, TPD52L2 | FBP1 2186/4885RAB9A 882/4885GBA1 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.