Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 17/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinimide SCHEMBL25397856 | 0.98 | HCAR3 (0.51) | HCAR3DDB1CRBNHCAR2GABRP | |
| Succinimide SCHEMBL27988812 | 0.96 | HCAR3 (0.53) | HCAR3DDB1CRBNHCAR2GABRP | |
| SCHEMBL28248953 | 0.90 | HCAR3 (0.47) | HCAR3DDB1CRBNHCAR2GABRP | |
| Succinimide SCHEMBL28645192 | 0.88 | NNMT (0.55) | — | |
| SCHEMBL29505896 | 0.87 | HCAR3 (0.67) | HCAR3HCAR2GABRPGABRDGABRA1 | |
| SCHEMBL158601 | 0.87 | HCAR3 (0.67) | HCAR3HCAR2GABRPGABRDGABRA1 | |
| Acetone SCHEMBL28225377 | 0.87 | HCAR3 (0.47) | HCAR3DDB1CRBNHCAR2 | |
| Hydrochloric Acid SCHEMBL5789616 | 0.85 | HCAR3 (0.65) | HCAR3HCAR2GABRPGABRDGABRA1 | |
| Ammonia Solution, Strong SCHEMBL28249483 | 0.85 | HCAR3 (0.65) | HCAR3HCAR2GABRPGABRDGABRA1 | |
| Succinimide SCHEMBL28224691 | 0.84 | NNMT (0.55) | HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586621-A | Targeting peptides are coupled to the method on recombination lysosomal enzyme | 阿米库斯治疗学公司 | 2018-09-28 | — | — | CN | claimed |
| CN-104160033-B | Method of coupling targeting peptides to recombinant lysosomal enzymes | 阿米库斯治疗学公司 | 2018-06-01 | — | — | CN | claimed |
| CN-108586621-A | Targeting peptides are coupled to the method on recombination lysosomal enzyme | 阿米库斯治疗学公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-104160033-B | Method of coupling targeting peptides to recombinant lysosomal enzymes | 阿米库斯治疗学公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-104892820-B | A kind of acceptor quasi-molecule targeted contrast agents and preparation method thereof | 厦门大学 | 2017-08-04 | — | — | CN | disclosed |